blood-brain barrier
51 episodes mention this concept
DocSnipesMar 18, 2026Physiological and Diagnostic Challenges of Addiction in Aging Adults
HealthCellular Age vs. Chronological AgePharmacokineticsDrug Half-lifeLiver and Kidney Clearance- DocSnipesMar 2, 2026
The Gut Microbiome and Mental Health: A Counselor's Guide to Understanding and Intervention
HealthGut microbiomeDysbiosisStress resilienceLeaky gut 
ChrisWillxJan 23, 2026Optimizing Circadian Rhythms to Combat Burnout and Enhance Sleep
HealthBurnout (two forms)Cortisol (chronically elevated, wrongly timed, square wave function)MelatoninCircadian rhythm
drekbergJan 23, 2026Early Signs of Chronic Toxicity: Understanding Modern Toxic Overload and Natural Detoxification
HealthChronic toxicityBlood-brain barrierOxidative stressMitochondrial dysfunction
hubermanlabJan 15, 2026Essentials: The Neuroscience of Memory, Attention, and Brain Health Through Exercise with Dr. Wendy Suzuki
NeuroscienceMemory encodingNovelty (memory)Repetition (memory)Association (memory)- ChrisWillxJan 14, 2026
The Evolving Landscape of Health: Supplements, Sobriety, and the Pursuit of True Expertise
HealthPublic acceptance cycleSupplementationCreatine loadingCreatine washout - hubermanlabJan 1, 2026
Optimizing Health & Longevity: Micronutrients, Hormesis, and Deliberate Stress with Dr. Rhonda Patrick
HealthHormesisStress response pathwaysHeat shock proteinsNRF2 pathway - hubermanlabAug 4, 2025
How to Control Your Cortisol & Overcome Burnout by Optimizing Your Circadian Rhythm
HealthCortisol rhythmCircadian rhythmBurnoutStress hormone (redefined) - DocSnipesJun 21, 2025
Stopping Inflammation from Ruining Your Mental Health: Stress, Brain Fog, and Aging
HealthInflammationAcute inflammationChronic inflammationStress response 
DrTraceyMarksJun 18, 2025The Critical Role of Hydration in Brain Function, Mental Clarity, and Resilience
HealthDehydration (mild)Cognitive performance impairmentFluid balanceElectrolyte balance- hubermanlabJun 5, 2025
The Science of Interoception: Strengthening Brain-Body Connection for Health and Performance
HealthInteroceptionSense of selfBrain-body communicationVagus nerve (10th cranial nerve) - DrTraceyMarksMay 28, 2025
Personalized Brain Nourishment: A Layered Approach to Food and Supplements for Resilience
HealthNutritional periodizationBaseline Boost Buffer frameworkNeurotransmittersAmino acids - hubermanlabMay 22, 2025
Optimizing Daily Physiology: Huberman Lab's Science-Based Protocols for Enhanced Health and Performance
HealthCircadian RhythmsTemperature MinimumForward AmbulationOptic Flow - DrTraceyMarksMay 7, 2025
Which Brain Supplements Actually Work: A Psychiatrist's Guide to 5 Effective and 3 Overhyped Options for Memory and Cognitive Health
HealthCognitive healthMemory supportNeurotransmittersBrain inflammation - drekbergApr 18, 2025
Beyond Superfoods: Destroying Inflammation by Addressing Root Causes and Optimizing Nutrient Bioavailability
HealthChronic inflammationInsulin resistanceNutrient deficienciesDysbiosis - drekbergMar 14, 2025
The Critical Role of Omega-3s and Fatty Acid Balance in Preventing Brain Degeneration and Chronic Disease
HealthOmega-3 fatty acidsEPA (Eicosapentaenoic acid)DHA (Docosahexaenoic acid)Omega-6 fatty acids - DocSnipesMar 7, 2025
Emerging Research in Schizophrenia: Unraveling Genetic, Neurological, Hormonal, and Gut-Brain Contributions
PsychologyGenetic foundations of schizophreniaNon-genetic factors in schizophreniaDopamine hypothesis (revisited)Neurotransmitter dysregulation - DocSnipesFeb 12, 2025
Revolutionary New Treatment Strategies for Depression: TMS, Anti-inflammatory Approaches, and Gut Microbiome
HealthTranscranial Magnetic Stimulation (TMS)NeuromodulationDorsal Lateral Prefrontal Cortex (DLPFC)Subgenual Anterior Cingulate Cortex - hubermanlabOct 21, 2024
The Pervasive Impact of Microplastics on Human Health and Actionable Mitigation Strategies
HealthMicroplasticsNanoplasticsBioaccumulationBlood-brain barrier (BBB) - DrTraceyMarksAug 21, 2024
Toxic Air: Hidden Dangers to Your Brain and Mental Health
HealthAir pollutionPM 2.5Gaseous pollutantsNitrogen oxides - drekbergAug 16, 2024
Intermittent Fasting and Exercise: A Multi-Mechanism Approach to Preventing and Reversing Dementia
HealthIntermittent FastingDementiaAlzheimer's DiseaseAmyloid Plaques - DocSnipesJun 14, 2024
Discover How Dopamine Impacts Serotonin, Hormones, and Happiness: A Holistic View
HealthDopamine (neurotransmitter)Blood-brain barrierMotivation chemicalDopamine receptors (D1, D2, D3) - DocSnipesJun 10, 2024
The Bidirectional Gut-Brain Axis: How the Second Brain Influences Mental and Physical Health
HealthGut-brain axisEnteric nervous system (ENS)Vagus nerveHPA axis (Hypothalamic-Pituitary-Adrenal axis) - drekbergApr 5, 2024
10 Urgent Signs of Magnesium Deficiency: Causes, Health Impacts, and Solutions
HealthMagnesium deficiencyCo-factor (enzymatic reactions)ATP (Adenosine Triphosphate)Calcium-magnesium balance - hubermanlabFeb 12, 2024
Oral Health as the Seventh Pillar: Its Profound Impact on Brain & Body Health
HealthOral microbiomeDemineralization (De Min)Remineralization (Remin)Enamel - DrTraceyMarksOct 25, 2023
L-Methylfolate: A B-Vitamin Solution for Treatment-Resistant Depression Linked to Inflammation
HealthTreatment-resistant depressionL-MethylfolateFolateFolic acid - hubermanlabJul 28, 2023
Kratom: Risks, Addiction Potential, and Opioid Mechanisms
HealthKratom (Mitragyna speciosa)Opioid crisisAddictionHabit-forming - hubermanlabJan 23, 2023
Optimizing Fertility: The Biology of Conception, Puberty Trends, and Lifespan Connections
HealthGerm cellsSomatic cellsSpermatogenesisOvulatory cycle - hubermanlabDec 8, 2022
Optimizing Deep Sleep: Behavioral and Supplemental Strategies for Enhanced Slow-Wave Sleep
HealthDeep Sleep (Slow-Wave Sleep)REM Sleep (Rapid Eye Movement Sleep)Sleep ArchitectureGrowth Hormone Release - DocSnipesNov 30, 2022
The Gut-Brain Axis: Its Profound Impact on Mental Health, Addiction Recovery, and Relapse Prevention
HealthGut-brain axisIntestinal microorganisms (gut microbiome)Neuroendocrine systemNeurotransmitters (serotonin, norepinephrine, dopamine, Gaba, acetylcholine) - hubermanlabSep 19, 2022
Nicotine's Nuanced Effects on Brain & Body: Focus, Addiction, and Strategies for Quitting Smoking & Vaping
HealthNicotineVapingSmokingAddiction - DocSnipesJul 28, 2022
Is Depression Caused by a Chemical Imbalance? A Multifactorial Perspective on Mood Regulation
PsychologySerotonin hypothesis of depressionSelective Serotonin Reuptake Inhibitors (SSRIs)5-HT receptorsSynaptic cleft - DocSnipesJul 21, 2022
Heat Stress and Mental Health: Physiological Impacts, Medication Interactions, and 20 Survival Tips
HealthHeat stressHPA axis activationSystemic inflammationDehydration - drekbergApr 15, 2022
The Absolute Best Way to Reverse and Slow Dementia: Understanding Mechanisms and Actionable Steps
HealthDementia (multifactorial)NeuroinflammationMicroglia (priming, persistent activation)Blood-brain barrier - hubermanlabMar 21, 2022
Controlling Sugar Cravings & Metabolism: The Nervous System's Role in Glucose Regulation and Brain Function
HealthNeurobiology of sugarSweet taste reinforcementNutritive content (sugar)Blood glucose regulation - drekbergFeb 25, 2022
Rethinking Cholesterol: Beyond Simplistic Labels and Statin Risks
HealthFamilial hypercholesterolemiaBlood-brain barrierCell membraneMyelin - DrTraceyMarksNov 24, 2021
What Exercise Does To Your Brain: Endocannabinoids, Neurogenesis, and Mood Enhancement
HealthRunner's highEndorphinsEndocannabinoidsBlood-brain barrier - drekbergOct 29, 2021
Microplastics in Bottled Water: Health Impacts, Environmental Crisis, and Solutions
HealthPlastic pollutionMicroplasticsNanoplasticsEndocrine disruptors - drekbergJun 11, 2021
The Top 10 Signs of Leaky Gut: Understanding Intestinal Permeability and Its Systemic Health Impacts
HealthLeaky Gut (Intestinal Permeability)Tight JunctionsDysbiosis (Unbalanced Gut Flora)Blood-Brain Barrier (BBB) 
lexfridmanJun 30, 2020Robert Langer: Pioneering Drug Delivery and Tissue Engineering
ScienceDrug delivery systemsTissue engineeringAngiogenesisPolymers- DocSnipesApr 11, 2020
Neurobiology of Addiction Part 2: Physiological Damage, Recovery, and Holistic Interventions
NeuroscienceHPA axis activationAdverse Childhood Experiences (ACEs)Emotional dysregulationNeurotoxicity - drekbergAug 26, 2019
Intermittent Fasting & Carb Requirements: Debunking Myths and Unveiling the Body's Fueling Genius
HealthIntermittent FastingCarbohydratesGlucoseKetones - drekbergJul 5, 2019
Autophagy Explained: The Science of Self-Eating for Longevity, Disease Reversal, and Optimal Health
HealthAutophagySelf-eatingCalorie restrictionLongevity - DocSnipesJan 10, 2019
Dopamine: Beyond the Pleasure Chemical - Its Multifaceted Roles, Imbalances, and Clinical Implications
NeuroscienceDopamineNeurotransmitterBlood-brain barrierL-dopa - DrTraceyMarksAug 8, 2018
Alternative Medicines for Anxiety: A Psychiatrist's Review of Non-Prescription Options
HealthAlternative medicineAnxiety disordersNon-prescription remediesRandomized controlled trials (RCTs) - DocSnipesMar 17, 2018
Demystifying Neurotransmitters: Serotonin, Dopamine, GABA, Norepinephrine, Glutamate, and Acetylcholine
NeuroscienceneurobiologyneurotransmittersdopamineGABA - drekbergMay 5, 2013
Mitochondria: The Powerhouse of Aging and Health - Understanding Energy, Free Radicals, and Protection
HealthMitochondriaATP (Adenosine Triphosphate)ADP (Adenosine Diphosphate)Free Radicals - hubermanlab
The Neurobiology and Physiological Impact of Salt on Thirst, Performance, and Health
HealthFluid balanceOsmolarityBlood-brain barrier (BBB)Organum Vasculosum of the Lamina Terminalis (OVLT) - hubermanlab
The Neurobiology of Salt: Optimizing Mental & Physical Performance, Thirst, and Cravings
HealthSodium regulationSalt appetiteBlood pressure regulationGut-brain axis - hubermanlab
The Comprehensive Impact of Alcohol on Brain, Body, and Behavior
HealthNeurodegenerationNeocortex thinningGray matterWhite matter - hubermanlab
The Nuanced Effects of Cannabis (Marijuana) on the Brain and Body: Compounds, Strains, and Individual Variability
NeuroscienceCannabis (Marijuana)THC (delta-9-tetrahydrocannabinol)CBD (cannabidiol)CBN (cannabinol)
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